Personalized Medicine in Cancer Treatment
Individual therapy decisions through molecular diagnostics and data-based analysis
Introducing the
research department
The Personalized Medicine department explores individualized therapy approaches based on molecular tumour profiles. The aim is to support practitioners in cancer medicine in initiating targeted therapies – tailored to the genetic characteristics of individual patients.
Data-based evaluations, AI-supported tools and access to complex molecular information are intended to optimize clinical decision-making in oncology. The focus here is on transferring innovative research findings into practice.
Molecular tumour board
The molecular profile of a tumour disease enables oncologists to initiate specialized, individualized therapy. The discussion and interpretation of the complex genomic findings takes place on an interdisciplinary basis in the Molecular Tumor Board (MTB) in collaboration with external clinics and laboratories, with additional identification of suitable clinical studies for oncology patients.
Research Team
Prof. Dr. med. Uwe Martens
Managing Director
Head of Personalized Medicine
In collaboration with the Clinical Research Group of the Tumorzentrum Heilbronn-Franken
Publications
Current Publications
from 2024
„A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine.“
Latzer P., Martens U.M., Illerhaus G., Sipos B., Zender L., Biskup S. (2024)
„A global, real world database of patients with a solid tumour profiled with next generation sequencing (NGS)“
Martens U.M., Blay J.-Y., Hackshaw A. et al.: WAYFIND R (2024)
„Off-label Einsatz von Trametinib/Palbociclib bei Patienten mit Metastasiertem Pankreaskarzinom: Ergebnisse einer unkontrollierten Fallserie als Beispiel für die Evidenzgenerierung aus Real-World-Daten“
Martens U.M., Vladimirova D., Bochum S., Berger S. (2024)
„Komplette Remission und Clearance zirkulierender Tumor-DNA (ctDNA) bei einem Patienten mit fortgeschrittenem Pankreaskarzinom nach einem adaptierten, personalisierten Ansatz“
Rohlfing S., Vladimirova D., Berger S., Bochum S., Martens U.M. et al. (2024)